Figures 2 and 3 illustrate the relations between age and rates of atrial fibrillation and stroke in more detail.Fig 1 chart of study populationAtrial fibrillationThe overall incidence of atrial fibrillation was approximately 40% higher in rheumatoid arthritis patients than in the general population (age and sex matched event rates of 8.2 and 6.0 per 1000 person years). Women were at slightly higher relative risk than men, and the relative risk of atrial fibrillation was markedly increased in the youngest age groups; the absolute risk attributable to rheumatoid arthritis ranged from 25% in the oldest to 70% in the youngest age group.The change in risk estimates after inclusion of baseline cardiovascular drug use and comorbidity in the analysis was negligible (table 3). The risk of atrial fibrillation associated with rheumatoid arthritis was somewhat reduced when all cardiovascular drug use and comorbidity was updated during follow up (incidence rate ratio 1.24, 95% confidence interval 1.15 to 1.35).
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